Abstract

Oncology patients undergoing cancer treatment experience an average of fifteen unrelieved symptoms that are highly variable in both their severity and distress. Recent advances in Network Analysis (NA) provide a novel approach to gain insights into the complex nature of co-occurring symptoms and symptom clusters and identify core symptoms. We present findings from the first study that used NA to examine the relationships among 38 common symptoms in a large sample of oncology patients undergoing chemotherapy. Using two different models of Pairwise Markov Random Fields (PMRF), we examined the nature and structure of interactions for three different dimensions of patients’ symptom experience (i.e., occurrence, severity, distress). Findings from this study provide the first direct evidence that the connections between and among symptoms differ depending on the symptom dimension used to create the network. Based on an evaluation of the centrality indices, nausea appears to be a structurally important node in all three networks. Our findings can be used to guide the development of symptom management interventions based on the identification of core symptoms and symptom clusters within a network. Document type: Article

Abstract

International standards for monitoring under ISO have been under development since 2010 and the intentions were presented during the 8th International Symposium on Field Monitoring in Geomechanics (FMGM 2011) in Berlin. Progress on this project was reported at FMGM 2015 in Sydney and ISFMG 2022 in London. The base standard on general rules was published in 2015, part 2, the standard on extensometers, in 2016 and in 2017 the third part on inclinometers. Part 4 on piezometers was published in 2020, Part 5 on pressure cells in 2019 and Part 8 on load cells in 2023. These standards have been published as ISO Standards in English and French worldwide. In Europe the standards have been published under EN ISO 18674 member countries of CEN have to publish these standards in their country. The standards on settlement measurements by hydraulic systems (part 6), geodetic measurements (part 9) and strain measurement (part 7) are under development and will be submitted to enquiry in the next few months.