Cruz Vargas-De-León is a Professor of Applied Maths and Biostatistics, and Researcher in Medical Sciences. His research interests are biostatistical and biomathematical modeling for health. He has published more than 80 articles, 60 of them in high-impact journals and JCR indexed. His global work has more than 1800 citations, according to Google Scholar. He has participated in the validation of surveys, randomized controlled trials, systematic reviews and meta-analyses, the construction of indices in medicine, the identification of immunological biomarkers in cancer and epidemiological studies. He is also a mathematical modeler of biological processes (infectious diseases, social epidemics, viral infections, antiviral immune response and mutualistic interactions between populations). He has participated in the Bayesian estimation of parameters of differential equation models. He has contributed to the theory of Lyapunov stability in differential equations of fractional order. He directed a thesis that obtained 2nd place in the Twenty-Second Mixbaal Prize Competition for the best Bachelor's thesis in Applied Mathematics of the Mexican Society of Scientific Computing and Its Applications (2024). He directed a thesis that obtained 3rd place in the "Francisco Aranda Ordaz" Thesis Competition at the master's level of the Mexican Statistics Association (2023). He received a certificate for highly cited research in Mathematical Biosciences (2016, Elsevier) and was awarded the Guillermo Soberón Guerrero State Award for Merit in Science and Technology (2016). His biography appeared in Marquis Who's Who in the World, Issue 30 (2013). Two of his articles received "excellent paper" awards from the National Program for Research Evaluation (2011‒2014) in Italy. He has been a member of the National System of Researchers (SNI, in Spanish) of Mexico’s National Council of Science and Technology (CONAHCYT, in Spanish) since 2015.