Research Lines & RTD Project in Biomedical Engineering

Research Lines & RTD Project in Biomedical Engineering

Centre Internacional de Metodes Numerics a l'Enginyeria - CIMNE, Barcelona, Spain

Research Lines & RTD Project in Biomedical Engineering:

Research Lines

in Biomedical Engineering

Computational Fluid Dynamics

Solid and Structural Biomechanics

Health Decision Support Systems

Cardiovascular System

Biomaterials

Artificial Intelligence

Neurosciences

Medical-GiD

Urology

Pre and post processing

* Stabilized finite element and finite difference methods in incompressible biofluid mechanics.

* Bio-Absorption theory application in vessel structures for atheroma plack and biochemical studies.

* Finite element methods for fluid flow and analysis.

* Numerical methods applied in multidisciplinary problems in fluid biomechanics (fluid structure interaction, thermal flows, absorption theory etc).

* Coupling 3D with 2D or 1D models to improve study details.

* Finite element methods for linear and non

linear analysis of solids structures.

* Coupled problems in solid biomechanics

(fluid structure interaction, thermal flows, absorption theory etc).

*

Finite element methods for biomechanical devices analysis and

prototype design (stent, prosthesis, etc).

* Finite element methods analysis of solid

biology structures (hearth mechanics,

vessel stresses response, etc).

* Development of intelligent platform to help physician work, informatization of routinely medical work.

* Finite element use to improve medical diagnosis and to perfect analysis processes.

* Biostatistical models applied ad hoc for several medical problems and cases.

*

Bioinformatic technology solutions to coupled finite elements methods with biostatistical tools and artificial intelligence.

* Monte-Carlo methods for stochastic analysis in computational biomechanics and in biofluid dynamics.

* Parameter identification via stochastic methods.

* Coupling of TIC solutions, stochastic methods and finite element methods to improve and get faster medical analysis and decision

*

Development of simulation platform for cardiovascular problems.

* Finite element for the simulation of problematic scenarios (aneurism, lumen obstruction, deformation, etc).

*

Finite element for the study of cholesterol and platelets vessel absorption.

* 1D-Vessel model of whole human body. General information coupled to specific 2D or 3D studies.

*

Reconstruction of real geometries starting by DICOM images.

* Automatic 2D and 3D geometries for vessel obstruction or aneurisms formation analysis.

*

Development of biocompatible geometries for internal or external devices (stents, internal prosthesis, etc).

* Finite element for stress testes with biomaterials and medical devices.

* Design and study of biocompatible devices for human medical use or experimental use.

*

New constitutive models for biomaterial and shape memory materials.

* Parameter identifications in constitutive

models of biomaterials.

*

Development of artificial neural networks (ANN) for optimization, inverse analysis and medical decision support fast decision taking.

* Integration of artificial neural networks (ANN) in decision support systems combining wireless sensors, computer simulations methods and artificial intelligence technology.

*

Development of artificial intelligence techniques based in agent simulations.

* Applications of artificial neural networks (ANN) technology for parameter identification in constitutive laws

* Development of intelligent finite element methods via Al Technology

http://www.cimne.com/flood/

*

Finite element methods for the analysis of brain cellular activity in pathological and physiological scenarios.

* 1D Finite element methods to study the propagations of neuronal signals in complex networks.

*

Statistical methods to fast response in biochemical brain analysis.

* Dementia diseases studies: finite element methods and bioinformatic solutions to reinforce the investigation about the causes of several brain dysfunction.

* Amyloids, Polymers and Cerebral Membrane Characterization

Edition/Generation

Meshing of heart and aorta

3D heart

*

Segmentation and 3D reconstruction

of medical images.

* Meshing of segmented geometries: creation of surface meshes or volume meshes.

* Visualization of 4D images (3D + time), creation of flux vectors and study of time developing in the image.

* Anatomical real cases.

* Coupling with simulation programs and with finite element methods solver.

* Friendly platform and portability of the informatics solutions adopted.

*

Finite Element Method for the simulation of the urinary bladder and its parts like the destrusor (little smooth muscle)

* Study of biological materials and its multi-scale hierarchy, creation of simplificated models with classical nonlinear continuum mechanics theory.

*

Characterization of destrusor-tissue model is based in the representation (based on hyperelastic matrix, and viscoelastic fibres)

*

Analisys of the interaction between bladder wall with urine modelled via the Particle Finite Element Method (PFE

* Development and maintenance of GiD pre and post processing system (www.gidhome.com).

* Development of methods for generating structure and unstructured meshes.

*

Development of input data technology for large scale computational problems.

* Graphical visualization techniques for large scale simulation problems.

* Generation of input data for finite element analysis from medical images.

* Meshless methods for parameterization of geometries for shape optimization problems.

www.gidhome.com

Research & Development Projects

in Biomedical Engineering

On going RTD projects:

Synapsys - NeuroInformatic-Support System for the Molecular Characterization and Therapeutic Approaches in SYNaptopathies

EUROPEAN COMMISSION, FP7

Coordinator: UIC

Partners: CIMNE, UIC, UL, Leibniz Institute of Polymers Research Dresden, Stockholm University, Università di Camerino, UniCAM, UAB, D-Pharma Ltd, NHIT, NBIO

(2009-2011)

Nynfa - Bio-Informatics Decision Support System for Characterization and Treatment of Neurological Diseases

Convocatoria: ayudas de proyectos de investigación fundamental no orientada

Coordinators UIC

Partners: CIMNE, UIC

2009-2011

CARE 4 ME - Cooperative Advanced REsearch for Medical Efficiency

Ente: ITEA 2 Information Technology for European Advancement

Coordinator: Philips HealthCare

Partners: Philips HealthCare, CIMNE, VTT, ISI, Alma IT Systems, Sapheneia, Fraunhofer MEVIS, Bull

Daedalus - The Virtual Dental Patient

EUROPEAN COMMISSION, FP7

Coordinator: Attenborough Dental Laboratories

Partners: Attenborough Dental Laboratories, CIMNE, Nottingham University, Aristotle University, FIMI Philips, DIGILEA SA

Finished RTD projects:

Estudio de soportes cardiovasculares Coordinator: IberHospitex

Partners: CIMNE, UPM, Tecknalia, Robotiker

2007-2008

SIMCV. - Simulación del comportamiento del corazón y periferia vascular en condiciones sanas y patológicas. Aplicación al diseño y evaluación de dispositivos intravasculares y válvulas cardiacas

Ref: DPI2004-07410-C03-02

MINISTERIO de EDUCACIÓN Y CIENCIA PLAN NACIONAL I+D

Coordinador: Universidad de Zaragoza

Partners Universidad de Zaragoza CIMNE, Universidad de Sevilla

2004-2007

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Disheart.DSS - Grid based decision support system for assisting clinical diagnosis and interventions in cardiovascular problems

EUROPEAN COMMISSION, FP6

Coordinador: CIMNE

Partners: I3A, Technical University Graz, TIMC-IMAG, COMPASS,HEARTCORE, George Mason University, ENDOART, QUANTECH (ES)

2003-2006

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