Line 46: Line 46:
  
  
[[Image:draft_Samper_526155048-image3.png|center|600px]]
+
[[Image:draft_Samper_526155048-image3.png|center|300px]]
  
 
<big>* Finite element methods for linear and non </big>
 
<big>* Finite element methods for linear and non </big>
Line 57: Line 57:
  
 
<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image9.png|center|600px]]
+
[[Image:draft_Samper_526155048-image9.png|center|300px]]
  
[[Image:draft_Samper_526155048-image10.png|center|600px]]
+
[[Image:draft_Samper_526155048-image10.png|center|300px]]
 
Finite element methods for biomechanical devices analysis and</big>
 
Finite element methods for biomechanical devices analysis and</big>
  
Line 71: Line 71:
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-picture-Group 20.svg|center|600px]]
+
[[Image:draft_Samper_526155048-picture-Group 20.svg|center|300px]]
 
</big>
 
</big>
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image17-c.png|center|600px]]
+
[[Image:draft_Samper_526155048-image17-c.png|center|300px]]
 
</big>
 
</big>
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image3.png|center|600px]]
+
[[Image:draft_Samper_526155048-image3.png|center|300px]]
 
</big>
 
</big>
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image19-c.png|center|600px]]
+
[[Image:draft_Samper_526155048-image19-c.png|center|300px]]
 
</big>
 
</big>
  
Line 103: Line 103:
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image24-c.png|center|600px]]
+
[[Image:draft_Samper_526155048-image24-c.png|center|300px]]
  
[[Image:draft_Samper_526155048-image25-c.png|center|600px]]
+
[[Image:draft_Samper_526155048-image25-c.png|center|300px]]
 
</big>
 
</big>
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image3.png|center|600px]]
+
[[Image:draft_Samper_526155048-image3.png|center|300px]]
 
</big>
 
</big>
  
 
<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image27.png|center|600px]]
+
[[Image:draft_Samper_526155048-image27.png|center|300px]]
  
[[Image:draft_Samper_526155048-image28-c.png|center|600px]]
+
[[Image:draft_Samper_526155048-image28-c.png|center|300px]]
 
Development of simulation platform for cardiovascular problems.</big>
 
Development of simulation platform for cardiovascular problems.</big>
  
Line 121: Line 121:
  
 
<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image29.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image29.jpeg|center|300px]]
 
Finite element for the study of cholesterol and platelets vessel absorption.</big>
 
Finite element for the study of cholesterol and platelets vessel absorption.</big>
  
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<big>* '''
 
<big>* '''
[[Image:draft_Samper_526155048-image30.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image30.jpeg|center|300px]]
 
'''Reconstruction of real geometries starting by DICOM images.</big>
 
'''Reconstruction of real geometries starting by DICOM images.</big>
  
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<big>
 
<big>
[[Image:draft_Samper_526155048-image31.png|center|600px]]
+
[[Image:draft_Samper_526155048-image31.png|center|300px]]
 
</big>
 
</big>
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image32.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image32.jpeg|center|300px]]
 
</big>
 
</big>
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image33.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image33.jpeg|center|300px]]
 
</big>
 
</big>
  
  
[[Image:draft_Samper_526155048-image3.png|center|600px]]
+
[[Image:draft_Samper_526155048-image3.png|center|300px]]
  
 
<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image35.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image35.jpeg|center|300px]]
  
[[Image:draft_Samper_526155048-image36.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image36.jpeg|center|300px]]
 
Development of biocompatible geometries for internal or external devices (stents, internal prosthesis, etc).</big>
 
Development of biocompatible geometries for internal or external devices (stents, internal prosthesis, etc).</big>
  
Line 158: Line 158:
  
 
<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image37.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image37.jpeg|center|300px]]
 
New constitutive models for biomaterial and shape memory materials.</big>
 
New constitutive models for biomaterial and shape memory materials.</big>
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image38.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image38.jpeg|center|300px]]
 
</big>
 
</big>
  
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<big>
 
<big>
[[Image:draft_Samper_526155048-image39.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image39.jpeg|center|300px]]
 
</big>
 
</big>
  
 
<div style="text-align: right; direction: ltr; margin-left: 1em;">
 
<div style="text-align: right; direction: ltr; margin-left: 1em;">
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image40.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image40.jpeg|center|300px]]
 
</big></div>
 
</big></div>
  
  
[[Image:draft_Samper_526155048-image3.png|center|600px]]
+
[[Image:draft_Samper_526155048-image3.png|center|300px]]
  
 
<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image42.png|center|600px]]
+
[[Image:draft_Samper_526155048-image42.png|center|300px]]
 
Development of artificial neural networks (ANN) for optimization, inverse analysis and medical decision support fast decision taking.</big>
 
Development of artificial neural networks (ANN) for optimization, inverse analysis and medical decision support fast decision taking.</big>
  
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<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image43.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image43.jpeg|center|300px]]
 
Development of artificial intelligence techniques based in agent simulations.</big>
 
Development of artificial intelligence techniques based in agent simulations.</big>
  
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<div style="text-align: right; direction: ltr; margin-left: 1em;">
 
<div style="text-align: right; direction: ltr; margin-left: 1em;">
  
[[Image:draft_Samper_526155048-image44.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image44.jpeg|center|300px]]
 
</div>
 
</div>
  
 
<div style="text-align: right; direction: ltr; margin-left: 1em;">
 
<div style="text-align: right; direction: ltr; margin-left: 1em;">
  
[[Image:draft_Samper_526155048-image45.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image45.jpeg|center|300px]]
 
</div>
 
</div>
  
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<big>
 
<big>
[[Image:draft_Samper_526155048-image3.png|center|600px]]
+
[[Image:draft_Samper_526155048-image3.png|center|300px]]
 
</big>
 
</big>
  
 
<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image47.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image47.jpeg|center|300px]]
 
Finite element methods for the analysis of brain cellular activity in pathological and physiological scenarios.</big>
 
Finite element methods for the analysis of brain cellular activity in pathological and physiological scenarios.</big>
  
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<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image48.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image48.jpeg|center|300px]]
 
Statistical methods to fast response in biochemical brain analysis.</big>
 
Statistical methods to fast response in biochemical brain analysis.</big>
  
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[[Image:draft_Samper_526155048-image49.png|center|600px]]
+
[[Image:draft_Samper_526155048-image49.png|center|300px]]
  
[[Image:draft_Samper_526155048-image50.png|center|600px]]
+
[[Image:draft_Samper_526155048-image50.png|center|300px]]
  
 
<div style="text-align: right; direction: ltr; margin-left: 1em;">
 
<div style="text-align: right; direction: ltr; margin-left: 1em;">
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image3.png|center|600px]]
+
[[Image:draft_Samper_526155048-image3.png|center|300px]]
 
</big></div>
 
</big></div>
  
  
[[Image:draft_Samper_526155048-image3.png|center|600px]]
+
[[Image:draft_Samper_526155048-image3.png|center|300px]]
  
 
==Magnetic Resonance (2D) ==
 
==Magnetic Resonance (2D) ==
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[[Image:draft_Samper_526155048-image52.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image52.jpeg|center|300px]]
  
[[Image:draft_Samper_526155048-image53.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image53.jpeg|center|300px]]
  
[[Image:draft_Samper_526155048-image54.png|center|600px]]
+
[[Image:draft_Samper_526155048-image54.png|center|300px]]
  
[[Image:draft_Samper_526155048-image55.png|center|600px]]
+
[[Image:draft_Samper_526155048-image55.png|center|300px]]
  
[[Image:draft_Samper_526155048-image56.png|center|600px]]
+
[[Image:draft_Samper_526155048-image56.png|center|300px]]
  
 
==Deformable isosurface model==
 
==Deformable isosurface model==
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[[Image:draft_Samper_526155048-image57-c.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image57-c.jpeg|center|300px]]
  
  
[[Image:draft_Samper_526155048-image58-c.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image58-c.jpeg|center|300px]]
  
 
==Meshing of heart==
 
==Meshing of heart==
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<big>
 
<big>
[[Image:draft_Samper_526155048-image3.png|center|600px]]
+
[[Image:draft_Samper_526155048-image3.png|center|300px]]
 
</big>
 
</big>
  
 
<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image60.png|center|600px]]
+
[[Image:draft_Samper_526155048-image60.png|center|300px]]
 
Segmentation and 3D reconstruction </big>
 
Segmentation and 3D reconstruction </big>
  
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<big>
 
<big>
[[Image:draft_Samper_526155048-image61.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image61.jpeg|center|300px]]
  
[[Image:draft_Samper_526155048-image62-c.png|center|600px]]
+
[[Image:draft_Samper_526155048-image62-c.png|center|300px]]
  
[[Image:draft_Samper_526155048-image63.png|center|600px]]
+
[[Image:draft_Samper_526155048-image63.png|center|300px]]
 
</big>
 
</big>
  
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<big>
 
<big>
[[Image:draft_Samper_526155048-image64-c.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image64-c.jpeg|center|300px]]
 
</big>
 
</big>
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image65-c.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image65-c.jpeg|center|300px]]
 
</big>
 
</big>
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image66-c.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image66-c.jpeg|center|300px]]
 
</big>
 
</big>
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image3.png|center|600px]]
+
[[Image:draft_Samper_526155048-image3.png|center|300px]]
 
</big>
 
</big>
  
 
<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image68.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image68.jpeg|center|300px]]
  
[[Image:draft_Samper_526155048-image69.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image69.jpeg|center|300px]]
 
Finite Element Method for the simulation of the urinary bladder and its parts like the destrusor (little smooth muscle)</big>
 
Finite Element Method for the simulation of the urinary bladder and its parts like the destrusor (little smooth muscle)</big>
  
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<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image70.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image70.jpeg|center|300px]]
 
Characterization of destrusor-tissue model is based in the representation (based on hyperelastic matrix, and viscoelastic fibres)</big>
 
Characterization of destrusor-tissue model is based in the representation (based on hyperelastic matrix, and viscoelastic fibres)</big>
  
 
<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image73.png|center|600px]]
+
[[Image:draft_Samper_526155048-image73.png|center|300px]]
 
Analisys of the interaction between bladder wall with urine modelled via the Particle Finite Element Method (PFE</big>
 
Analisys of the interaction between bladder wall with urine modelled via the Particle Finite Element Method (PFE</big>
  
 
<big>
 
<big>
[[Image:draft_Samper_526155048-image3.png|center|600px]]
+
[[Image:draft_Samper_526155048-image3.png|center|300px]]
 
</big>
 
</big>
  
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<big>*  
 
<big>*  
[[Image:draft_Samper_526155048-image74.png|center|600px]]
+
[[Image:draft_Samper_526155048-image74.png|center|300px]]
  
[[Image:draft_Samper_526155048-image75.png|center|600px]]
+
[[Image:draft_Samper_526155048-image75.png|center|300px]]
  
[[Image:draft_Samper_526155048-image76.png|center|600px]]
+
[[Image:draft_Samper_526155048-image76.png|center|300px]]
 
Development of input data technology for large scale computational problems.</big>
 
Development of input data technology for large scale computational problems.</big>
  
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<big>
 
<big>
[[Image:draft_Samper_526155048-image77.png|center|600px]]
+
[[Image:draft_Samper_526155048-image77.png|center|300px]]
 
</big>
 
</big>
  
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<div style="text-align: right; direction: ltr; margin-left: 1em;">
 
<div style="text-align: right; direction: ltr; margin-left: 1em;">
 
<big>'''
 
<big>'''
[[Image:draft_Samper_526155048-picture-Group 65.svg|center|600px]]
+
[[Image:draft_Samper_526155048-picture-Group 65.svg|center|300px]]
 
'''<br/></big></div>
 
'''<br/></big></div>
  
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<div class="center" style="width: auto; margin-left: auto; margin-right: auto;">
 
<div class="center" style="width: auto; margin-left: auto; margin-right: auto;">
 
'''
 
'''
[[Image:draft_Samper_526155048-image87-c.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image87-c.jpeg|center|300px]]
  
[[Image:draft_Samper_526155048-image88-c.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image88-c.jpeg|center|300px]]
 
'''</div>
 
'''</div>
  
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==
 
==
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+
[[Image:draft_Samper_526155048-image89-c.png|center|300px]]
 
==
 
==
  
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==
 
==
[[Image:draft_Samper_526155048-image90-c.jpeg|center|600px]]
+
[[Image:draft_Samper_526155048-image90-c.jpeg|center|300px]]
 
==
 
==

Revision as of 16:13, 26 January 2017

Research Lines & RTD Project in Biomedical Engineering

Centre Internacional de Metodes Numerics a l'Enginyeria - CIMNE, Barcelona, Spain



Research Lines & RTD Project in Biomedical Engineering:

Computational Fluid Dynamics
Solid and Structural Biomechanics
Health Decision Support Systems
Cardiovascular System
Biomaterials
Artificial Intelligence
Neurosciences
Medical-GiD
Urology
Pre and post processing


Draft Samper 526155048-image3.png

* Stabilized finite element and finite difference methods in incompressible biofluid mechanics.

* Bio-Absorption theory application in vessel structures for atheroma plack and biochemical studies.

* Finite element methods for fluid flow and analysis.

Draft Samper 526155048-image4.png
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* Numerical methods applied in multidisciplinary problems in fluid biomechanics (fluid structure interaction, thermal flows, absorption theory etc).

* Coupling 3D with 2D or 1D models to improve study details.


Draft Samper 526155048-image3.png

* Finite element methods for linear and non

linear analysis of solids structures.

* Coupled problems in solid biomechanics

(fluid structure interaction, thermal flows, absorption theory etc).

*

Draft Samper 526155048-image9.png
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Finite element methods for biomechanical devices analysis and

prototype design (stent, prosthesis, etc).

* Finite element methods analysis of solid

biology structures (hearth mechanics,

vessel stresses response, etc).

Draft Samper 526155048-picture-Group 20.svg

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* Development of intelligent platform to help physician work, informatization of routinely medical work.

* Finite element use to improve medical diagnosis and to perfect analysis processes.

* Biostatistical models applied ad hoc for several medical problems and cases.

*

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Bioinformatic technology solutions to coupled finite elements methods with biostatistical tools and artificial intelligence.

* Monte-Carlo methods for stochastic analysis in computational biomechanics and in biofluid dynamics.

* Parameter identification via stochastic methods.

* Coupling of TIC solutions, stochastic methods and finite element methods to improve and get faster medical analysis and decision

Draft Samper 526155048-image24-c.png
Draft Samper 526155048-image25-c.png

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*

Draft Samper 526155048-image27.png
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Development of simulation platform for cardiovascular problems.

* Finite element for the simulation of problematic scenarios (aneurism, lumen obstruction, deformation, etc).

*

Draft Samper 526155048-image29.jpeg

Finite element for the study of cholesterol and platelets vessel absorption.

* 1D-Vessel model of whole human body. General information coupled to specific 2D or 3D studies.

*

Draft Samper 526155048-image30.jpeg

Reconstruction of real geometries starting by DICOM images.

* Automatic 2D and 3D geometries for vessel obstruction or aneurisms formation analysis.

Draft Samper 526155048-image31.png

Draft Samper 526155048-image32.jpeg

Draft Samper 526155048-image33.jpeg


Draft Samper 526155048-image3.png

*

Draft Samper 526155048-image35.jpeg
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Development of biocompatible geometries for internal or external devices (stents, internal prosthesis, etc).

* Finite element for stress testes with biomaterials and medical devices.

* Design and study of biocompatible devices for human medical use or experimental use.

*

Draft Samper 526155048-image37.jpeg

New constitutive models for biomaterial and shape memory materials.

Draft Samper 526155048-image38.jpeg

* Parameter identifications in constitutive

models of biomaterials.

Draft Samper 526155048-image39.jpeg

Draft Samper 526155048-image40.jpeg


Draft Samper 526155048-image3.png

*

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Development of artificial neural networks (ANN) for optimization, inverse analysis and medical decision support fast decision taking.

* Integration of artificial neural networks (ANN) in decision support systems combining wireless sensors, computer simulations methods and artificial intelligence technology.

*

Draft Samper 526155048-image43.jpeg

Development of artificial intelligence techniques based in agent simulations.

* Applications of artificial neural networks (ANN) technology for parameter identification in constitutive laws

* Development of intelligent finite element methods via Al Technology

Draft Samper 526155048-image44.jpeg
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http://www.cimne.com/flood/

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*

Draft Samper 526155048-image47.jpeg

Finite element methods for the analysis of brain cellular activity in pathological and physiological scenarios.

* 1D Finite element methods to study the propagations of neuronal signals in complex networks.

*

Draft Samper 526155048-image48.jpeg

Statistical methods to fast response in biochemical brain analysis.

* Dementia diseases studies: finite element methods and bioinformatic solutions to reinforce the investigation about the causes of several brain dysfunction.

* Amyloids, Polymers and Cerebral Membrane Characterization


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Magnetic Resonance (2D)

2D Detail

Edition/Generation

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Deformable isosurface model

Meshing of heart and aorta

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Meshing of heart

3D heart

Draft Samper 526155048-image3.png

*

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Segmentation and 3D reconstruction

of medical images.

* Meshing of segmented geometries: creation of surface meshes or volume meshes.

* Visualization of 4D images (3D + time), creation of flux vectors and study of time developing in the image.

Draft Samper 526155048-image61.jpeg
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* Anatomical real cases.

* Coupling with simulation programs and with finite element methods solver.

* Friendly platform and portability of the informatics solutions adopted.

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*

Draft Samper 526155048-image68.jpeg
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Finite Element Method for the simulation of the urinary bladder and its parts like the destrusor (little smooth muscle)

* Study of biological materials and its multi-scale hierarchy, creation of simplificated models with classical nonlinear continuum mechanics theory.

*

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Characterization of destrusor-tissue model is based in the representation (based on hyperelastic matrix, and viscoelastic fibres)

*

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Analisys of the interaction between bladder wall with urine modelled via the Particle Finite Element Method (PFE

Draft Samper 526155048-image3.png

* Development and maintenance of GiD pre and post processing system (www.gidhome.com).

* Development of methods for generating structure and unstructured meshes.

*

Draft Samper 526155048-image74.png
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Development of input data technology for large scale computational problems.

* Graphical visualization techniques for large scale simulation problems.

* Generation of input data for finite element analysis from medical images.

* Meshless methods for parameterization of geometries for shape optimization problems.

Draft Samper 526155048-image77.png

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www.gidhome.com

Research & Development Projects
in Biomedical Engineering

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On going RTD projects:

Synapsys - NeuroInformatic-Support System for the Molecular Characterization and Therapeutic Approaches in SYNaptopathies

EUROPEAN COMMISSION, FP7

Coordinator: UIC

Partners: CIMNE, UIC, UL, Leibniz Institute of Polymers Research Dresden, Stockholm University, Università di Camerino, UniCAM, UAB, D-Pharma Ltd, NHIT, NBIO

(2009-2011)

Nynfa - Bio-Informatics Decision Support System for Characterization and Treatment of Neurological Diseases

Convocatoria: ayudas de proyectos de investigación fundamental no orientada

Coordinators UIC

Partners: CIMNE, UIC

2009-2011

CARE 4 ME - Cooperative Advanced REsearch for Medical Efficiency

Ente: ITEA 2 Information Technology for European Advancement

Coordinator: Philips HealthCare

Partners: Philips HealthCare, CIMNE, VTT, ISI, Alma IT Systems, Sapheneia, Fraunhofer MEVIS, Bull

Daedalus - The Virtual Dental Patient

EUROPEAN COMMISSION, FP7

Coordinator: Attenborough Dental Laboratories

Partners: Attenborough Dental Laboratories, CIMNE, Nottingham University, Aristotle University, FIMI Philips, DIGILEA SA

Finished RTD projects:

Estudio de soportes cardiovasculares Coordinator: IberHospitex

Partners: CIMNE, UPM, Tecknalia, Robotiker

2007-2008

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SIMCV. - Simulación del comportamiento del corazón y periferia vascular en condiciones sanas y patológicas. Aplicación al diseño y evaluación de dispositivos intravasculares y válvulas cardiacas

Ref: DPI2004-07410-C03-02

MINISTERIO de EDUCACIÓN Y CIENCIA PLAN NACIONAL I+D

Coordinador: Universidad de Zaragoza

Partners Universidad de Zaragoza CIMNE, Universidad de Sevilla

2004-2007

==

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==

Disheart.DSS - Grid based decision support system for assisting clinical diagnosis and interventions in cardiovascular problems

EUROPEAN COMMISSION, FP6

Coordinador: CIMNE

Partners: I3A, Technical University Graz, TIMC-IMAG, COMPASS,HEARTCORE, George Mason University, ENDOART, QUANTECH (ES)

2003-2006

==

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==

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