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==Research Lines & RTD Project in Biomedical Engineering==
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=Research Lines & RTD Project in Biomedical Engineering=
  
 
Computational Fluid Dynamics<br />
 
Computational Fluid Dynamics<br />
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[[Image:draft_Samper_526155048-image4.png|center|150px]]
 
[[Image:draft_Samper_526155048-image4.png|center|150px]]
  
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|[[Image:draft_Samper_526155048-image7.jpeg|center|300px]]
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[[Image:draft_Samper_526155048-image5.jpeg|center|300px]]
 
[[Image:draft_Samper_526155048-image5.jpeg|center|300px]]
  
 +
 +
==Solid and Structural Biomechanics==
  
 
<big>* Finite element methods for linear and non  
 
<big>* Finite element methods for linear and non  
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<big>* Coupled problems in solid biomechanics (fluid structure interaction, thermal flows, absorption theory etc). </big>
 
<big>* Coupled problems in solid biomechanics (fluid structure interaction, thermal flows, absorption theory etc). </big>
  
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<big>*
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[[Image:draft_Samper_526155048-image9.png|center|300px]]
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|[[Image:draft_Samper_526155048-image9.png|center|300px]]
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|[[Image:draft_Samper_526155048-image10.png|center|300px]]
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|}
  
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[[Image:draft_Samper_526155048-image10.png|center|300px]]
 
  
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Finite element methods for biomechanical devices analysis and prototype design (stent,  prosthesis, etc).</big>
+
<big>* Finite element methods for biomechanical devices analysis and prototype design (stent,  prosthesis, etc).</big>
  
 
<big>* Finite element methods analysis of solid  
 
<big>* Finite element methods analysis of solid  
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|style="padding:10px";|[[File:Draft_Samper_526155048_9412_graf-rueda.png|center|500px]]
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<big>
 
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[[Image:draft_Samper_526155048-image17-c.png|center|300px]]
 
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</big>
 
  
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<big>
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==Health Decision Support System==
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[[Image:draft_Samper_526155048-image19-c.png|center|300px]]
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−
</big>
+
  
 
<big>* Development of intelligent platform to help physician work, informatization of routinely medical work.</big>
 
<big>* Development of intelligent platform to help physician work, informatization of routinely medical work.</big>
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<big>* Biostatistical models applied ad hoc for several medical problems and cases.</big>
 
<big>* Biostatistical models applied ad hoc for several medical problems and cases.</big>
  
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<big>*
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<big>
−
[[Image:draft_Samper_526155048-picture-Group 111.svg|center|266px]]
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[[Image:draft_Samper_526155048-image19-c.png|center|300px]]
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Bioinformatic technology solutions to coupled finite elements methods with biostatistical tools and artificial intelligence.</big>
+
</big>
 +
 
 +
 
 +
<big>* Bioinformatic technology solutions to coupled finite elements methods with biostatistical tools and artificial intelligence.</big>
  
 
<big>* Monte-Carlo methods for stochastic analysis in computational biomechanics and in biofluid dynamics.</big>
 
<big>* Monte-Carlo methods for stochastic analysis in computational biomechanics and in biofluid dynamics.</big>
  
 
<big>* Parameter identification via stochastic methods.</big>
 
<big>* Parameter identification via stochastic methods.</big>
 +
 +
[[Image:draft_Samper_526155048-picture-Group 111.svg|center|266px]]
  
 
<big>* Coupling of TIC solutions, stochastic methods and finite element methods to improve and get faster medical analysis and decision</big>
 
<big>* Coupling of TIC solutions, stochastic methods and finite element methods to improve and get faster medical analysis and decision</big>
  
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<big>
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[[Image:draft_Samper_526155048-image24-c.png|center|300px]]
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|[[Image:draft_Samper_526155048-image24-c.png|center|300px]]
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|style="padding:10px;"|[[Image:draft_Samper_526155048-image25-c.png|center|300px]]
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|}
  
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[[Image:draft_Samper_526155048-image25-c.png|center|300px]]
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==Computational Fluid Dynamics==
−
</big>
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−
 
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<big>* Development of simulation platform for cardiovascular problems.</big>
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<big>*  
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[[Image:draft_Samper_526155048-image27.png|center|300px]]
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−
 
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[[Image:draft_Samper_526155048-image28-c.png|center|300px]]
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Development of simulation platform for cardiovascular problems.</big>
+
  
 
<big>* Finite element for the simulation of problematic scenarios (aneurism, lumen obstruction, deformation, etc).</big>
 
<big>* Finite element for the simulation of problematic scenarios (aneurism, lumen obstruction, deformation, etc).</big>
  
−
<big>*  
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<big>* Finite element for the study of cholesterol and platelets vessel absorption.</big>
−
[[Image:draft_Samper_526155048-image29.jpeg|center|300px]]
+
−
Finite element for the study of cholesterol and platelets vessel absorption.</big>
+
  
 
<big>* 1D-Vessel model of whole human body. General information coupled to specific 2D or 3D studies. </big>
 
<big>* 1D-Vessel model of whole human body. General information coupled to specific 2D or 3D studies. </big>
  
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<big>* '''
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{|
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[[Image:draft_Samper_526155048-image30.jpeg|center|300px]]
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|-
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'''Reconstruction of real geometries starting by DICOM images.</big>
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|style="padding:15px;"|[[Image:draft_Samper_526155048-image27.png|center|150px]]
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|[[Image:draft_Samper_526155048-image28-c.png|center|150px]]
 +
|style="padding:15px;"|[[Image:draft_Samper_526155048-image29.jpeg|center|150px]]
 +
|}
 +
 
 +
<big>* Reconstruction of real geometries starting by DICOM images.</big>
  
 
<big>* Automatic 2D and 3D geometries for vessel obstruction or aneurisms formation analysis.</big>
 
<big>* Automatic 2D and 3D geometries for vessel obstruction or aneurisms formation analysis.</big>
  
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<big>
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[[Image:draft_Samper_526155048-image30.jpeg|center|300px]]
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[[Image:draft_Samper_526155048-image31.png|center|300px]]
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</big>
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<big>
 
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[[Image:draft_Samper_526155048-image32.jpeg|center|300px]]
 
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</big>
 
  
 
<big>
 
<big>
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[[Image:draft_Samper_526155048-image33.jpeg|center|300px]]
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[[Image:draft_Samper_526155048-image31.png|center|500px]]
 
</big>
 
</big>
  
 +
==Biomaterials==
  
−
<big>*
+
Development of biocompatible geometries for internal or external devices (stents, internal prosthesis, etc).
−
[[Image:draft_Samper_526155048-image35.jpeg|center|300px]]
+
−
 
+
−
[[Image:draft_Samper_526155048-image36.jpeg|center|300px]]
+
−
Development of biocompatible geometries for internal or external devices (stents, internal prosthesis, etc).</big>
+
  
 
<big>* Finite element for stress testes with biomaterials and medical devices.</big>
 
<big>* Finite element for stress testes with biomaterials and medical devices.</big>
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<big>*  
 
<big>*  
−
[[Image:draft_Samper_526155048-image37.jpeg|center|300px]]
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[[Image:draft_Samper_526155048-image35.jpeg|center|300px]]
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New constitutive models for biomaterial and shape memory materials.</big>
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−
 
+
−
<big>
+
−
[[Image:draft_Samper_526155048-image38.jpeg|center|300px]]
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</big>
 
</big>
  
−
<big>* Parameter identifications in constitutive </big>
 
  
−
<big>models of biomaterials.</big>
+
<big>* New constitutive models for biomaterial and shape memory materials.</big>
  
−
<big>
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<big>* Parameter identifications in constitutive models of biomaterials.</big>
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[[Image:draft_Samper_526155048-image39.jpeg|center|300px]]
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−
</big>
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<div style="text-align: right; direction: ltr; margin-left: 1em;">
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[[Image:draft_Samper_526155048-image37.jpeg|center|300px]]
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<big>
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[[Image:draft_Samper_526155048-image40.jpeg|center|300px]]
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</big></div>
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{| style="text-align: center;"
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|-
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|[[Image:draft_Samper_526155048-image38.jpeg|center|300px]]
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|[[Image:draft_Samper_526155048-image39.jpeg|center|300px]]
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|-
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|[[Image:draft_Samper_526155048-image40.jpeg|center|350px]]
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|[[Image:draft_Samper_526155048-image36.jpeg|center|200px]]
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|}
 +
 +
==Artifial Intelligence==
  
 
<big>*  
 
<big>*  
−
[[Image:draft_Samper_526155048-image42.png|center|300px]]
 
 
Development of artificial neural networks (ANN) for optimization, inverse analysis and medical decision support fast decision taking.</big>
 
Development of artificial neural networks (ANN) for optimization, inverse analysis and medical decision support fast decision taking.</big>
 +
 +
[[Image:draft_Samper_526155048-image42.png|center|300px]]
  
 
<big>* Integration of artificial neural networks (ANN) in decision support systems combining wireless sensors, computer simulations methods and artificial intelligence technology.</big>
 
<big>* Integration of artificial neural networks (ANN) in decision support systems combining wireless sensors, computer simulations methods and artificial intelligence technology.</big>
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<big>* Development of intelligent finite element methods via Al Technology</big>
 
<big>* Development of intelligent finite element methods via Al Technology</big>
  
−
<div style="text-align: right; direction: ltr; margin-left: 1em;">
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{| style="text-align: center;"
 +
|-
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|[[Image:draft_Samper_526155048-image45.jpeg|center|300px]]
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| [[Image:draft_Samper_526155048-image44.jpeg|center|300px]]
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|-
 +
| [http://www.cimne.com/flood/ http://www.cimne.com/flood/]
 +
|
 +
|}
  
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[[Image:draft_Samper_526155048-image44.jpeg|center|300px]]
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==Neursciences==
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</div>
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<div style="text-align: right; direction: ltr; margin-left: 1em;">
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<big>*
 +
Finite element methods for the analysis of brain cellular activity in pathological and physiological scenarios.</big>
  
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[[Image:draft_Samper_526155048-image45.jpeg|center|300px]]
 
−
</div>
 
−
 
−
<big>'''          [http://www.cimne.com/flood/ http://www.cimne.com/flood/]'''</big>
 
−
 
−
 
−
<big>*
 
 
[[Image:draft_Samper_526155048-image47.jpeg|center|300px]]
 
[[Image:draft_Samper_526155048-image47.jpeg|center|300px]]
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Finite element methods for the analysis of brain cellular activity in pathological and physiological scenarios.</big>
 
  
 
<big>* 1D Finite element methods to study the propagations of neuronal signals in complex networks.</big>
 
<big>* 1D Finite element methods to study the propagations of neuronal signals in complex networks.</big>
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[[Image:draft_Samper_526155048-image49.png|center|300px]]
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|[[Image:draft_Samper_526155048-image50.png|center|300px]]
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| style="padding-left:20px;"| [[Image:draft_Samper_526155048-image49.png|center|300px]]
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|}
  
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[[Image:draft_Samper_526155048-image50.png|center|300px]]
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==Medical-GiD==
  
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<div style="text-align: right; direction: ltr; margin-left: 1em;">
 
  
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[[Image:draft_Samper_526155048-image3.png|center|300px]]</div>
 
  
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{| style="text-align: center; "
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|-
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| [[Image:draft_Samper_526155048-image53.jpeg|center|300px]]
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|style="padding:15px;"|[[Image:draft_Samper_526155048-image54.png|center|300px]]
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|[[Image:draft_Samper_526155048-image52.jpeg|center|300px]]
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|-
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|Magnetic Resonance (2D)
 +
| 2D Detail
 +
|Edition/Generation
 +
|}
  
  
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===Magnetic Resonance (2D) ===
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{| style="text-align: center; "
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|-
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|[[Image:draft_Samper_526155048-image55.png|center|300px]]
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|style="padding:15px;"|[[Image:draft_Samper_526155048-image56.png|center|250px]]
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|-
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|Deformable isosurface model
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|Meshing of heart and aorta
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|-
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|[[Image:draft_Samper_526155048-image58-c.jpeg|center|300px]]
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|style="padding:15px;"|[[Image:draft_Samper_526155048-image57-c.jpeg|center|200px]]
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|-
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|Meshing of heart
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|3D heart
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|}
  
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[[Image:draft_Samper_526155048-image52.jpeg|center|300px]]
 
  
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===2D Detail===
 
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[[Image:draft_Samper_526155048-image53.jpeg|center|300px]]
 
  
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===Edition/Generation===
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<big>* Segmentation and 3D reconstruction of medical images. </big>
  
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[[Image:draft_Samper_526155048-image54.png|center|300px]]
 
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===Deformable isosurface model===
 
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[[Image:draft_Samper_526155048-image55.png|center|300px]]
 
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===Meshing of heart and aorta===
 
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[[Image:draft_Samper_526155048-image56.png|center|300px]]
 
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===Meshing of heart===
 
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[[Image:draft_Samper_526155048-image57-c.jpeg|center|300px]]
 
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===3D heart===
 
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[[Image:draft_Samper_526155048-image58-c.jpeg|center|300px]]
 
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−
 
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<big>*
 
 
[[Image:draft_Samper_526155048-image60.png|center|300px]]
 
[[Image:draft_Samper_526155048-image60.png|center|300px]]
−
Segmentation and 3D reconstruction </big>
 
  
−
<big>  of medical images. </big>
 
  
 
<big>* Meshing of segmented geometries: creation of surface meshes or volume meshes.</big>
 
<big>* Meshing of segmented geometries: creation of surface meshes or volume meshes.</big>
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<big>* Visualization of 4D images (3D + time), creation of flux vectors and study of time developing in the image.</big>
 
<big>* Visualization of 4D images (3D + time), creation of flux vectors and study of time developing in the image.</big>
  
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<big>
 
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[[Image:draft_Samper_526155048-image61.jpeg|center|300px]]
 
  
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[[Image:draft_Samper_526155048-image62-c.png|center|300px]]
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[[File:Draft_Samper_526155048_2501_FigIT573.png|center]]
  
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[[Image:draft_Samper_526155048-image63.png|center|300px]]
 
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</big>
 
  
 
<big>* Anatomical real cases.</big>
 
<big>* Anatomical real cases.</big>
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<big>* Friendly platform and portability of the informatics solutions adopted.</big>
 
<big>* Friendly platform and portability of the informatics solutions adopted.</big>
  
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<big>
 
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[[Image:draft_Samper_526155048-image64-c.jpeg|center|300px]]
 
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</big>
 
  
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{| style="text-align: center; "
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[[Image:draft_Samper_526155048-image65-c.jpeg|center|300px]]
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</big>
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|[[Image:draft_Samper_526155048-image65-c.jpeg|center|300px]]
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|style="padding:15px;"|[[Image:draft_Samper_526155048-image64-c.jpeg|center|300px]]
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|[[Image:draft_Samper_526155048-image66-c.jpeg|center|300px]]
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|}
  
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<big>
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==Urology==
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[[Image:draft_Samper_526155048-image66-c.jpeg|center|300px]]
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</big>
+
  
  
−
<big>*  
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<big>* Finite Element Method for the simulation of the urinary bladder and its parts like the destrusor (little smooth muscle)</big>
−
[[Image:draft_Samper_526155048-image68.jpeg|center|300px]]
+
 
 +
<big>* Study of biological materials and its multi-scale hierarchy, creation of simplificated models with classical nonlinear continuum mechanics theory. </big>
 +
 
  
 
[[Image:draft_Samper_526155048-image69.jpeg|center|300px]]
 
[[Image:draft_Samper_526155048-image69.jpeg|center|300px]]
−
Finite Element Method for the simulation of the urinary bladder and its parts like the destrusor (little smooth muscle)</big>
 
  
−
<big>* Study of biological materials and its multi-scale hierarchy, creation of simplificated models with classical nonlinear continuum mechanics theory. </big>
 
  
−
<big>*  
+
<big>* Characterization of destrusor-tissue model is based in the representation (based on hyperelastic matrix, and viscoelastic fibres)</big>
 +
 
 +
 
 
[[Image:draft_Samper_526155048-image70.jpeg|center|300px]]
 
[[Image:draft_Samper_526155048-image70.jpeg|center|300px]]
−
Characterization of destrusor-tissue model is based in the representation (based on hyperelastic matrix, and viscoelastic fibres)</big>
 
  
−
<big>*
 
−
[[Image:draft_Samper_526155048-image73.png|center|300px]]
 
−
Analisys of the interaction between bladder wall with urine modelled via the Particle Finite Element Method (PFE</big>
 
  
 +
<big>* Analisys of the interaction between bladder wall with urine modelled via the Particle Finite Element Method (PFEM) </big>
 +
 +
{|
 +
|-
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| [[Image:draft_Samper_526155048-image73.png|center|300px]]
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|style="padding:15px;"|[[Image:draft_Samper_526155048-image68.jpeg|center|300px]]
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|}
 +
 +
==Pre and Post Proccesing==
  
 
<big>* Development and maintenance of GiD pre and post processing system ([http://www.gidhome.com www.gidhome.com]).</big>
 
<big>* Development and maintenance of GiD pre and post processing system ([http://www.gidhome.com www.gidhome.com]).</big>
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<big>* Development of methods for generating structure and unstructured meshes.</big>
 
<big>* Development of methods for generating structure and unstructured meshes.</big>
  
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<big>*  
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<big>* Development of input data technology for large scale computational problems.</big>
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[[Image:draft_Samper_526155048-image74.png|center|300px]]
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[[Image:draft_Samper_526155048-image75.png|center|300px]]
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[[Image:draft_Samper_526155048-image76.png|center|300px]]
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Development of input data technology for large scale computational problems.</big>
+
  
 
<big>* Graphical visualization techniques for large scale simulation problems.</big>
 
<big>* Graphical visualization techniques for large scale simulation problems.</big>
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<big>* Meshless methods for parameterization of geometries for shape optimization problems.</big>
 
<big>* Meshless methods for parameterization of geometries for shape optimization problems.</big>
  
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<big>
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[[Image:draft_Samper_526155048-image75.png|center|300px]]
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[[Image:draft_Samper_526155048-image77.png|center|300px]]
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</big>
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<big>
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[[Image:draft_Samper_526155048-image76.png|center|300px]]
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[[Image:draft_Samper_526155048-picture-Group 106.svg|center|265px]]
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</big>
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[[Image:draft_Samper_526155048-image74.png|center|300px]]
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[[File:Draft_Samper_526155048_1299_Fig2IT573.png|center|300px]]
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<div class="center">
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[[Image:draft_Samper_526155048-image77.png|center|250px]]
  
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<big>[http://www.gidhome.com www.gidhome.com]     </big>
+
[http://www.gidhome.com www.gidhome.com] </div>

Latest revision as of 13:10, 13 June 2018

Research Lines & RTD Project in Biomedical Engineering

Computational Fluid Dynamics
Solid and Structural Biomechanics
Health Decision Support Systems
Cardiovascular System
Biomaterials
Artificial Intelligence
Neurosciences
Medical-GiD
Urology
Pre and post processing


Computational Fluid Dynamics

* Stabilized finite element and finite difference methods in incompressible biofluid mechanics.

* Bio-Absorption theory application in vessel structures for atheroma plack and biochemical studies.

* Finite element methods for fluid flow and analysis.

Draft Samper 526155048-image4.png
Draft Samper 526155048-image7.jpeg
Draft Samper 526155048-image6.jpeg

* Numerical methods applied in multidisciplinary problems in fluid biomechanics (fluid structure interaction, thermal flows, absorption theory etc).

* Coupling 3D with 2D or 1D models to improve study details.

Draft Samper 526155048-image5.jpeg


Solid and Structural Biomechanics

* Finite element methods for linear and non linear analysis of solids structures.

* Coupled problems in solid biomechanics (fluid structure interaction, thermal flows, absorption theory etc).

Draft Samper 526155048-image9.png
Draft Samper 526155048-image10.png


* Finite element methods for biomechanical devices analysis and prototype design (stent, prosthesis, etc).

* Finite element methods analysis of solid biology structures (hearth mechanics, vessel stresses response, etc).


Draft Samper 526155048-image17-c.png
Draft Samper 526155048 9412 graf-rueda.png


Health Decision Support System

* Development of intelligent platform to help physician work, informatization of routinely medical work.

* Finite element use to improve medical diagnosis and to perfect analysis processes.

* Biostatistical models applied ad hoc for several medical problems and cases.

Draft Samper 526155048-image19-c.png


* Bioinformatic technology solutions to coupled finite elements methods with biostatistical tools and artificial intelligence.

* Monte-Carlo methods for stochastic analysis in computational biomechanics and in biofluid dynamics.

* Parameter identification via stochastic methods.

Draft Samper 526155048-picture-Group 111.svg

* Coupling of TIC solutions, stochastic methods and finite element methods to improve and get faster medical analysis and decision

Draft Samper 526155048-image24-c.png
Draft Samper 526155048-image25-c.png

Computational Fluid Dynamics

* Development of simulation platform for cardiovascular problems.

* Finite element for the simulation of problematic scenarios (aneurism, lumen obstruction, deformation, etc).

* Finite element for the study of cholesterol and platelets vessel absorption.

* 1D-Vessel model of whole human body. General information coupled to specific 2D or 3D studies.

Draft Samper 526155048-image27.png
Draft Samper 526155048-image28-c.png
Draft Samper 526155048-image29.jpeg

* Reconstruction of real geometries starting by DICOM images.

* Automatic 2D and 3D geometries for vessel obstruction or aneurisms formation analysis.

Draft Samper 526155048-image30.jpeg


Draft Samper 526155048-image31.png

Biomaterials

Development of biocompatible geometries for internal or external devices (stents, internal prosthesis, etc).

* Finite element for stress testes with biomaterials and medical devices.

* Design and study of biocompatible devices for human medical use or experimental use.

*

Draft Samper 526155048-image35.jpeg


* New constitutive models for biomaterial and shape memory materials.

* Parameter identifications in constitutive models of biomaterials.

Draft Samper 526155048-image37.jpeg


Draft Samper 526155048-image38.jpeg
Draft Samper 526155048-image39.jpeg
Draft Samper 526155048-image40.jpeg
Draft Samper 526155048-image36.jpeg

Artifial Intelligence

* Development of artificial neural networks (ANN) for optimization, inverse analysis and medical decision support fast decision taking.

Draft Samper 526155048-image42.png

* Integration of artificial neural networks (ANN) in decision support systems combining wireless sensors, computer simulations methods and artificial intelligence technology.

*

Draft Samper 526155048-image43.jpeg

Development of artificial intelligence techniques based in agent simulations.

* Applications of artificial neural networks (ANN) technology for parameter identification in constitutive laws

* Development of intelligent finite element methods via Al Technology

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http://www.cimne.com/flood/

Neursciences

* Finite element methods for the analysis of brain cellular activity in pathological and physiological scenarios.

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* 1D Finite element methods to study the propagations of neuronal signals in complex networks.

*

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Statistical methods to fast response in biochemical brain analysis.

* Dementia diseases studies: finite element methods and bioinformatic solutions to reinforce the investigation about the causes of several brain dysfunction.

* Amyloids, Polymers and Cerebral Membrane Characterization


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Medical-GiD

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Magnetic Resonance (2D) 2D Detail Edition/Generation


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Deformable isosurface model Meshing of heart and aorta
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Meshing of heart 3D heart


* Segmentation and 3D reconstruction of medical images.

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* Meshing of segmented geometries: creation of surface meshes or volume meshes.

* Visualization of 4D images (3D + time), creation of flux vectors and study of time developing in the image.


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* Anatomical real cases.

* Coupling with simulation programs and with finite element methods solver.

* Friendly platform and portability of the informatics solutions adopted.


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Urology

* Finite Element Method for the simulation of the urinary bladder and its parts like the destrusor (little smooth muscle)

* Study of biological materials and its multi-scale hierarchy, creation of simplificated models with classical nonlinear continuum mechanics theory.


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* Characterization of destrusor-tissue model is based in the representation (based on hyperelastic matrix, and viscoelastic fibres)


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* Analisys of the interaction between bladder wall with urine modelled via the Particle Finite Element Method (PFEM)

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Pre and Post Proccesing

* Development and maintenance of GiD pre and post processing system (www.gidhome.com).

* Development of methods for generating structure and unstructured meshes.

* Development of input data technology for large scale computational problems.

* Graphical visualization techniques for large scale simulation problems.

* Generation of input data for finite element analysis from medical images.

* Meshless methods for parameterization of geometries for shape optimization problems.

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www.gidhome.com
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